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Red blood cell storage affects the stability of cytosolic native protein complexes.

著者 Pallotta V , Rinalducci S , Zolla L
Transfusion.2015 Mar 21 ; ():.
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Refrigerated storage of red blood cell (RBC) units promotes the progressive accumulation of the so-called storage lesions, a widespread series of alterations to morphology, metabolism, and proteome integrity of stored RBCs. However, while storage lesions targeting the RBC membrane fraction have been widely documented, the cytosolic fraction is as yet an underinvestigated cause of the technical inconveniences related to the high abundance of hemoglobin.
PMID: 25808351 [PubMed - as supplied by publisher]
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