絞り込み

17897

広告

A kidney transplant recipient with renal medullary viral cytopathic changes.

著者 Ramanan P , Timmerman EA , Fidler ME , Amer H , Pritt BS , Schwab DA , Batterman HJ , Binnicker MJ
Transpl Infect Dis.2016 Dec 07 ; ():.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (9view , 0users)

Full Text Sources

Medical

We present a case of JC polyomavirus (JCV)-associated nephropathy (PyVAN) in an asymptomatic deceased-donor kidney transplant recipient. Despite the presence of viral cytopathic effect in the kidney biopsy and positive BK polyomavirus (BKV) in situ hybridization (ISH), BKV real-time polymerase chain reaction (PCR) results of plasma and urine were negative. JCV ISH was performed and was found to be positive. JCV real-time PCR on urine, plasma, and the kidney biopsy tissue was positive. Reduction in immunosuppression resulted in resolution of JCV viremia. This case highlights that JC-PyVAN is a distinct clinical entity and is likely to have a better clinical outcome than BK-PyVAN. Concurrent infection with BKV and JCV may occur, but may be difficult to confirm owing to the potential for cross reactivity between BKV and JCV IHS stains. This article is protected by copyright. All rights reserved.
PMID: 27925350 [PubMed - as supplied by publisher]
印刷用ページを開く Endnote用テキストダウンロード