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Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

著者 Wang Z , Singh R , Miller BE , Tal-Singer R , Van Horn S , Tomsho L , Mackay A , Allinson JP , Webb AJ , Brookes AJ , George LM , Barker B , Kolsum U , Donnelly LE , Belchamber K , Barnes PJ , Singh D , Brightling CE , Donaldson GC , Wedzicha JA , Brown J
Thorax.2017 Dec 21 ; ():.
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Recent studies suggest that lung microbiome dysbiosis, the disease associated disruption of the lung microbial community, might play a key role in chronic obstructive pulmonary disease (COPD) exacerbations. However, characterising temporal variability of the microbiome from large longitudinal COPD cohorts is needed to better understand this phenomenon.
PMID: 29269441 [PubMed - as supplied by publisher]
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