絞り込み

16735

広告

Stretching Single Titin Molecules from Failing Human Hearts Reveals Titin's Role in Blunting Cardiac Kinetic Reserve.

著者 Chen MP , Kiduko SA , Saad NS , Canan BD , Kilic A , Mohler PJ , Janssen PML
Cardiovasc Res.2019 Feb 18 ; ():.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (1view , 0users)

Full Text Sources

Miscellaneous

Heart failure patients commonly experience symptoms primarily during elevated heart rates, as a result of physical activities or stress. A main determinant of diastolic passive tension, the elastic sarcomeric protein titin, has been shown to be associated with heart failure, with unresolved involvement regarding its role at different heart rates. To determine whether titin is playing a role in the heart rate (frequency-) dependent acceleration of relaxation (FDAR). W, we studied the FDAR responses in live human left ventricular cardiomyocytes and the corresponding titin-based passive tension (TPT) from failing and non-failing human hearts.
PMID: 30778519 [PubMed - as supplied by publisher]
印刷用ページを開く Endnote用テキストダウンロード