絞り込み

16643

広告

Ceramides in Parkinson's Disease: From Recent Evidence to New Hypotheses.

著者 Plotegher N , Bubacco L , Greggio E , Civiero L
Front Neurosci.2019 ; 13():330.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (111view , 0users)

Full Text Sources

Ceramides (Cer) constitute a class of lipids present in the cell membranes where they act as structural components, but they can also work as signaling molecules. Increasing genetic and biochemical evidence supports a link between deregulation of ceramide metabolism in the brain and neurodegeneration. Here, we provide an overview of the genes and cellular pathways that link Cer with Parkinson's disease and discuss how ceramide pathobiology is gaining increasing interest in the understanding of the pathological mechanisms that contribute to the disease and in the clinical and therapeutic side.
PMID: 31001082 [PubMed]
印刷用ページを開く Endnote用テキストダウンロード