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Evolution and clustering of prodromal parkinsonian features in GBA1 carriers.

著者 Mullin S , Beavan M , Bestwick J , McNeill A , Proukakis C , Cox T , Hughes D , Mehta A , Zetterberg H , Schapira AHV
Mov Disord.2019 Jun 28 ; ():.
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Five to 25% of patients with PD carry glucocerebrosidase gene mutations, and 10% to 30% of glucocerebrosidase carriers will develop PD by age 80. Stratification of PD risk in glucocerebrosidase carriers provides an opportunity to target disease-modifying therapies.
PMID: 31251436 [PubMed - as supplied by publisher]
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