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Dipeptidyl-peptidase-4 as a marker of activated fibroblasts and a potential target for the treatment of fibrosis in Systemic Sclerosis.

著者 Soare A , Györfi HA , Matei AE , Dees C , Rauber S , Wohlfahrt T , Chen CW , Ludolph I , Horch RE , Bäuerle T , von Hörsten S , Mihai C , Distler O , Ramming A , Schett G , Distler JHW
Arthritis Rheumatol.2019 Jul 26 ; ():.
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Dipeptidyl-peptidase-4 (DPP4) identifies a dermal fibroblast lineage involved in scaring during wound healing. The role of DDP4 in tissue fibrosis, however, is unknown. The aim of the present study was to evaluate DPP4 as a potential target for the treatment of fibrosis in systemic sclerosis (SSc).
PMID: 31350829 [PubMed - as supplied by publisher]
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