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Targeted sequencing identifies the mutational signature of double primary and metastatic malignancies: a case report.

著者 Rao C , Nie L , Miao X , Lizaso A , Zhao G
Diagn Pathol.2019 Sep 04 ; 14(1):101.
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The accurate identification of the tissue of origin is critical for optimal management of cancer patients particularly those who develop multiple malignancies; however, conventional diagnostic methods at times may fail to provide conclusive diagnosis of the origin of the malignancy. Herein, we describe the use of targeted sequencing in distinguishing the primary and metastatic tumors in a patient with metachronous malignancies in the lung, colon and kidney.
PMID: 31484545 [PubMed - in process]
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