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Vildagliptin and G-CSF Improved Angiogenesis and Survival after Acute Myocardial Infarction.

著者 Li M , Wang Z , Xia H , Yu L , Hu Z
Arch Med Res.2019 Apr ; 50(3):133-141.
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Myocardial infarction (MI) is one of the most important diseases that has stimulated interest in understanding cardiac function recovery. SDF-1 is a chemotactic factor and a pro-angiogenic molecule; SDF-1 degradation is inhibited by dipeptidyl peptidase-4 (DPP4) inhibitors, such as vildagliptin. We investigated whether vildagliptin affects angiogenesis in MI and improves cardiac function recovery.
PMID: 31495390 [PubMed - in process]
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