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Critical Assessment in Routine Clinical Practice of Liquid Biopsy for EGFR Status Testing in Non-Small-Cell Lung Cancer: A Single-Laboratory Experience (LPCE, Nice, France).

著者 Heeke S , Benzaquen J , Hofman V , Ilié M , Allegra M , Long-Mira E , Lassalle S , Tanga V , Salacroup C , Bonnetaud C , Fayada J , Gazoppi L , Ribeyre L , Castelnau O , Garnier G , Cattet F , Nanni I , de Fraipont F , Cohen C , Berthet JP , Leroy S , Pou
Clin Lung Cancer.2019 Aug 03 ; ():.
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The introduction of liquid biopsy using PCR-based assays into routine practice has had a strong impact on the treatment of EGFR-mutated lung adenocarcinoma and is now commonly used for routine testing of EGFR mutations in certain clinical settings. To assess whether the claimed benefits of PCR-based assays hold true in daily practice at a multicenter clinical institution, we assessed how treatment decisions are affected by PCR-based assays for the analysis of EGFR mutations from plasma samples in a centralized laboratory (LPCE, Nice, France).
PMID: 31519454 [PubMed - as supplied by publisher]
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