絞り込み

16641

広告

【動画】今日はどうされましたか? (日経BP)

診察室やカンファレンスなどでよく使う医療英語のエッセンスを、今日も楽しく学んでいきましょう。 今日のトレーニングは「最初の3単語」です。診察室でよく使うこのフレ...

  1. 地域包括ケア病棟 (日経BP)
  2. 預かった保険証を紛失! 心当たりをたどる...
  3. 製薬会社からのギフトは処方に影響するか?...
  4. ホルモン受容体陽性進行乳癌へのCDK4/...

ニュース一覧

Incidence of Delayed Bleeding among Patients Continuing Antithrombotics during Gastric Endoscopic Submucosal Dissection.

著者 Kakushima N , Ono H , Takizawa K , Tanaka M , Kawata N , Yoshida M , Murai K , Yabuuchi Y , Kishida Y , Ito S , Imai K , Hotta K , Ishiwatari H , Matsubayashi H
Intern Med.2019 ; 58(19):2759-2766.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (22view , 0users)

Full Text Sources

Miscellaneous

objective In patients continuing antithrombotics, delayed bleeding after gastric endoscopic submucosal dissection (ESD) is a severe complication. Vonoprazan (VPZ) exerts a rapid, potent, and long-lasting antacid effect compared with traditional proton-pump inhibitors (PPIs). This study aimed to compare the incidence of delayed bleeding after gastric ESD between the use of VPZ and PPIs in patients continuing antithrombotics. Methods In this retrospective analysis, we examined 71 patients with 101 lesions treated with traditional PPIs (PPI group) and 59 patients with 90 lesions treated with VPZ (VPZ group). After 2 days (day 0 and 1) of intravenous PPI administration, either an oral PPI or VPZ was administered from postoperative day 2 to 8 weeks after ESD. We assessed the incidence of overall delayed bleeding as well as bleeding that occurred from day 2 until 8 weeks after ESD. Results There was no significant difference in the use of antithrombotic agents between the groups. Overall delayed bleeding occurred 13 times (18%) in 9 patients in the PPI group and 18 times (31%) in 17 patients in the VPZ group (p=0.10). Bleeding from day 2 until 8 weeks after ESD occurred 12 times (17%) in 9 patients in the PPI group and 8 times (14%) in 8 patients in the VPZ group. Conclusion Even with a potent antacid agent, such as VPZ, the incidence of delayed bleeding was high in patients undergoing ESD with continuous antithrombotic agents.
PMID: 31582592 [PubMed - in process]
印刷用ページを開く Endnote用テキストダウンロード