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Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer.

著者 Liang C , Shi S , Qin Y , Meng Q , Hua J , Hu Q , Ji S , Zhang B , Xu J , Yu XJ
Gut.2019 Oct 14 ; ():.
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Pancreatic ductal adenocarcinoma (PDAC) is the most aggressive type of GI tumour, and it possesses deregulated cellular energetics. Although recent advances in PDAC biology have led to the discovery of recurrent genetic mutations in , and , which are related to this disease, clinical application of the molecular phenotype of PDAC remains challenging.
PMID: 31611300 [PubMed - as supplied by publisher]
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