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Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells.

著者 Dai Z , Song G , Balakrishnan A , Yang T , Yuan Q , Möbus S , Weiss AC , Bentler M , Zhu J , Jiang X , Shen X , Bantel H , Jaeckel E , Kispert A , Vogel A , Saborowski A , Büning H , Manns M , Cantz T , Ott M , Sharma AD
Gut.2019 Nov 25 ; ():.
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Liver fibrosis and cirrhosis resulting from chronic liver injury represent a major healthcare burden worldwide. Growth differentiation factor (GDF) 11 has been recently investigated for its role in rejuvenation of ageing organs, but its role in chronic liver diseases has remained unknown. Here, we investigated the expression and function of GDF11 in liver fibrosis, a common feature of most chronic liver diseases.
PMID: 31767630 [PubMed - as supplied by publisher]
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