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Distance effect characteristic of the matrix attachment region increases recombinant protein expression in Chinese hamster ovary cells.

著者 Zhang JH , Zhang JH , Wang XY , Xu DH , Wang TY
Biotechnol Lett.2019 Nov 27 ; ():.
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Previously, we have found that the matrix attachment region (MAR) may confer a 'distance effect' on transgene expression. This work aims to systematically explore the increased transgene expression in transfected Chinese hamster ovary (CHO) cells due to the characteristics of MAR and its mechanism.
PMID: 31776751 [PubMed - as supplied by publisher]
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