絞り込み

18450

広告

「核ごみ」国、初の住民説明会 理解求める 北海道・神恵内村 (毎日新聞)

高レベル放射性廃棄物(核のごみ)最終処分場の選定に向けた文献調査応募の動きがある北海道神恵内(かもえない)村で26日夜、資源エネルギー庁と原子力発電環境整備機構...

  1. 「日韓交流おまつり」初のオンライン開催 ...
  2. [医学] HIV感染の恐れが大きい人の1...
  3. [医学] PTEN欠損胆管細胞癌にプロテ...
  4. [医学] α1抗トリプシン欠乏変異の人が...

ニュース一覧

Immune Activation in Functional Gastrointestinal Disorders.

著者 Burns G , Pryor J , Holtmann G , Walker MM , Talley NJ , Keely S
Gastroenterol Hepatol (N Y).2019 Oct ; 15(10):539-548.
この記事をPubMed上で見るPubMedで表示
この記事をGoogle翻訳上で見る Google翻訳で開く

スターを付ける スターを付ける     (14view , 0users)
There is growing appreciation that functional gastrointestinal disorders (FGIDs) such as functional dyspepsia and irritable bowel syndrome are heterogeneous conditions linked by subtle inflammation within the gastrointestinal (GI) tract. The literature suggests that while the symptoms of these diseases may manifest with similar clinical presentations, there are significant differences in triggers and disease severity among patients classified into the same subtype. It is hypothesized that the subtle inflammation observed in these patients is related to an imbalance in GI homeostasis. Disruption of the delicate homeostatic balance within the GI tract can result from any number or combination of factors, including dysbiosis, loss of barrier integrity, genetic predisposition, or immune responses to dietary or luminal antigens. This article discusses the interplay between the immune system, microbiota, and luminal environment in FGIDs. In addition, the article proposes emerging immune pathways, including those involving T-helper type 17 response and innate lymphoid cells, as potential regulators of the subtle inflammation characteristic of FGIDs that warrant investigation in future studies.
PMID: 31802978 [PubMed]
印刷用ページを開く Endnote用テキストダウンロード