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Inhibition of human cervical cancer cell invasion by IL-37 involving runt related transcription factor 2 suppression.

著者 Ouyang P , Wu K , Su L , An W , Bie Y , Zhang H , Kang H , Jiang E , Zhu W , Yao Y , Hu X , Chen Z , Wang S
Ann Transl Med.2019 Oct ; 7(20):568.
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IL-37 is a newly anti-inflammatory cytokine whose function is largely unknown in cancer. Our preliminary experiment found IL-37 could inhibit the invasion of human cervical cancer (CC) cells and influence the expression of RUNX family whose function was also unclear in CC. The present study aims to further investigate the effects of IL-37 on cell invasion and runt related transcription factor 2 (RUNX2) expression in CC cell lines.
PMID: 31807549 [PubMed]
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