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Weeds had caused significant loss for crop production in the process of agriculture. Herbicides have played an important role in securing the crop production. However, the high reliance on herbicides has led to environment issues as well as to the evolution of herbicide resistance. So, there is an urgent need for new herbicides with safer toxicological profiles and novel modes of action. Actinomycetes produce very diverse bioactive compounds, of which some show potent biopesticidal activity. The herbicidal secondary metabolites from actinomycetes can be classified into several groups such as amino acids, peptides, nucleosides, macrolides, lactones, amide and amines, etc., some of which have been successfully developed as commercial herbicides. The structure diversity and evolved biological activity of secondary metabolites from actinomycetes can offer opportunities for the development of both directly used bioherbicides and synthetic herbicides with new target sites, and so this review focuses on the structure, herbicidal activity and mode of actions of secondary metabolites from actinomycetes.
PMID: 31809036 [PubMed - as supplied by publisher]