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Recurrent chromosomal rearrangements of , and activating JAK/STAT pathway in inflammatory hepatocellular adenomas.

著者 Bayard Q , Caruso S , Couchy G , Rebouissou S , Bioulac Sage P , Balabaud C , Paradis V , Sturm N , de Muret A , Guettier C , Bonsang B , Copie C , Letouzé E , Calderaro J , Imbeaud S , Nault JC , Zucman-Rossi J
Gut.2020 Jan 06 ; ():.
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Inflammatory hepatocellular adenomas (IHCAs) are benign liver tumours characterised by an activation of the janus kinase (JAK)/signal transducers and activators of transcription (STAT) pathway caused by oncogenic activating mutations. However, a subset of IHCA lacks of identified mutation explaining the inflammatory phenotype.
PMID: 31907296 [PubMed - as supplied by publisher]
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