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Modification effects of temperature on the ozone-mortality relationship: a nationwide multicounty study in China.

著者 Shi W , Sun Q , Du P , Tang S , Chen C , Sun Z , Wang J , Li T , Shi X
Environ Sci Technol.2020 Feb 05 ; ():.
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Both ozone exposure and extreme temperatures are found to be significantly associated with mortality; however, inconsistent results have been obtained on the modification effects of temperatur on the ozone-mortality association. We conducted a nationwide time-series study in 128 counties from 2013-2018 to examine whether temperature modifies the association between short-term ozone exposure and nonaccidental and cause-specific mortality in China. First, we analyzed the effects of ozone exposure on mortality at different temperature levels. Then we calculated the pooled effects through a meta-analysis across China. We found that high-temperature conditions (>75th percentile in each county) significantly enhanced the effects of ozone on nonaccidental, cardiovascular and respiratory mortality, with increases of 0.44% (95% confidence interval (CI): 0.36%, 0.51%), 0.42% (95% CI: 0.32%, 0.51%) and 0.50% (95% CI: 0.31%, 0.68%), respectively, at a 10 μg/m3 increase in ozone under high-temperature conditions (>75th percentile in each county). The strongest effects on nonaccidental and cardiovascular mortality were observed at high temperatures among elderly individuals aged 65 years and older. Our findings provide evidence that health damage due to ozone may be influenced by the impacts of increasing temperatures, which point to the importance of mitigating ozone exposure in China under the context of climate change to further reduce the public health burden.
PMID: 32022552 [PubMed - as supplied by publisher]
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