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「"aaps j"[Journal]」の検索結果

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Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1.

Advancements in Understanding Immunogenicity of Biotherapeutics in the Intraocular Space.

Comparison of NMR and Dynamic Light Scattering for Measuring Diffusion Coefficients of Formulated Insulin: Implications for Particle Size Distribution Measurements in Drug Products.

Peripheral Nerve Nanoimaging: Monitoring Treatment and Regeneration.

Submicron Matrices Embedded in a Polymeric Caplet for Extended Intravaginal Delivery of Zidovudine.

Blood-Brain Barrier Driven Pharmacoresistance in Amyotrophic Lateral Sclerosis and Challenges for Effective Drug Therapies.

Data to Decisions: Creating a Culture of Model-Driven Drug Discovery.

Physicochemical Characterization of Iron Carbohydrate Colloid Drug Products.

Microdialysis as an Important Technique in Systems Pharmacology-a Historical and Methodological Review.

Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies.

Optimization and Application of a Biotinylation Method for Quantification of Plasma Membrane Expression of Transporters in Cells.

Recommendations for Systematic Statistical Computation of Immunogenicity Cut Points.

Clinical Evaluation of Modified Release and Immediate Release Tacrolimus Formulations.

Utility of Physiologically Based Pharmacokinetic Absorption Modeling to Predict the Impact of Salt-to-Base Conversion on Prasugrel HCl Product Bioequivalence in the Presence of Proton Pump Inhibitors.

Application of Exposure-Response Analyses to Establish the Pharmacodynamic Similarity of a Once-Daily Regimen to an Approved Twice-Daily Dosing Regimen for the Treatment of HCV Infection.

Pharmacokinetics and Pharmacogenomics of Bupropion in Three Different Formulations with Different Release Kinetics in Healthy Human Volunteers.

Biopharmaceutical Evaluation and CMC Aspects of Oral Modified Release Formulations.

SLC and ABC Transporters: Expression, Localization, and Species Differences at the Blood-Brain and the Blood-Cerebrospinal Fluid Barriers.

Microdialysis Coupled with LC-MS/MS for In Vivo Neurochemical Monitoring.

γ-Hydroxybutyric Acid (GHB) Pharmacokinetics and Pharmacodynamics: Semi-Mechanistic and Physiologically Relevant PK/PD Model.

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