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「"aaps j"[Journal]」の検索結果

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Identifying Metabolites of Meclonazepam by High-Resolution Mass Spectrometry Using Human Liver Microsomes, Hepatocytes, a Mouse Model, and Authentic Urine Samples.

Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers.

Approaches to Mitigate the Unwanted Immunogenicity of Therapeutic Proteins during Drug Development.

A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9.

Identification of New Synthetic Cannabinoid ADB-CHMINACA (MAB-CHMINACA) Metabolites in Human Hepatocytes.

Pharmacokinetics and Saturable Absorption of Gabapentin in Nursing Home Elderly Patients.

An Integrated Assessment of the Effects of Immunogenicity on the Pharmacokinetics, Safety, and Efficacy of Elotuzumab.

Influence of drug load and physical form of cinnarizine in new SNEDDS dosing regimens: in vivo and in vitro evaluations.

Porous mannitol carrier for pulmonary delivery of cyclosporine A nanoparticles.

Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development.

Immune Suppression During Preclinical Drug Development Mitigates Immunogenicity-Mediated Impact on Therapeutic Exposure.

Erratum to: Tumor Static Concentration Curves in Combination Therapy.

Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects Modeling.

Exposure-Response and Tumor Growth Inhibition Analyses of the Monovalent Anti-c-MET Antibody Onartuzumab (MetMAb) in the Second- and Third-Line Non-Small Cell Lung Cancer.

Cardiovascular Ion Channel Inhibitor Drug-Drug Interactions with P-glycoprotein.

Tissue Concentration of Dodecafluoropentane (DDFP) Following Repeated IV Administration in the New Zealand White Rabbit.

Optimal Affinity of a Monoclonal Antibody: Guiding Principles Using Mechanistic Modeling.

Bioavailability and Bioequivalence Aspects of Oral Modified-Release Drug Products.

Insulin Formulation Characterization-the Thioflavin T Assays.

Clinical Translation of the National Institutes of Health's Investments in Nanodrug Products and Devices.

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