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「"Isacson O "[Author]」の検索結果

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Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease.

Novel Results and Concepts Emerging From Lipid Cell Biology Relevant to Degenerative Brain Aging and Disease.

Comprehensive cell surface antigen analysis identifies transferrin receptor protein-1 (CD71) as a negative selection marker for human neuronal cells.

Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease.

Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.

Neurite Collapse and Altered ER Ca Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation.

Lipid-dependent deposition of alpha-synuclein and Tau on neuronal Secretogranin II-positive vesicular membranes with age.

The glycoprotein GPNMB is selectively elevated in the substantia nigra of Parkinson's disease patients and increases after lysosomal stress.

Glycosphingolipid levels and glucocerebrosidase activity are altered in normal aging of the mouse brain.

Increased motor neuron resilience by small molecule compound that regulate IGF-II expression.

Integrated molecular landscape of Parkinson's disease.

The Threshold Theory for Parkinson's Disease.

Parkinsonian Monkeys With Prior Levodopa-Induced Dyskinesias Followed by Fetal Dopamine Precursor Grafts Do Not Display Graft-Induced Dyskinesias.

hVMAT2: A Target of Individualized Medication for Parkinson's Disease.

Genetic Variants of Microtubule Actin Cross-linking Factor 1 (MACF1) Confer Risk for Parkinson's Disease.

Gene therapy by proteasome activator, PA28γ, improves motor coordination and proteasome function in Huntington's disease YAC128 mice.

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models.

In vivo modeling of neuronal function, axonal impairment and connectivity in neurodegenerative and neuropsychiatric disorders using induced pluripotent stem cells.

Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition.

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.

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