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「Nucleic Acids Res[Journal]」の検索結果

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Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells.

VarFish: comprehensive DNA variant analysis for diagnostics and research.

Encoding multiple digital DNA signals in a single analog channel.

High specificity and tight spatial restriction of self-biotinylation by DNA and RNA G-Quadruplexes complexed in vitro and in vivo with Heme.

Prediction of condition-specific regulatory genes using machine learning.

O-GlcNAc regulates gene expression by controlling detained intron splicing.

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs.

Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.

A distinct role for recombination repair factors in an early cellular response to transcription-replication conflicts.

Alternative proteins are functional regulators in cell reprogramming by PKA activation.

Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine modifications at non-palindromic recognition sites in Bacillus subtilis.

NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data.

MusiteDeep: a deep-learning based webserver for protein post-translational modification site prediction and visualization.

IKBKE activity enhances AR levels in advanced prostate cancer via modulation of the Hippo pathway.

TFmotifView: a webserver for the visualization of transcription factor motifs in genomic regions.

Specific histone modifications associate with alternative exon selection during mammalian development.

miRViz: a novel webserver application to visualize and interpret microRNA datasets.

Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.

Enabling large-scale genome editing at repetitive elements by reducing DNA nicking.

Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes.

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