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「現役女子高生 ピル飲んでます」誤解解いて ツイートに反響 (NHK)

女性の生理の痛みなどを和らげる治療薬としての低用量ピル。しかし避妊目的のイメージが強く、生理痛の治療に使うことが知られていないため、つらい思いをしたと訴える女子...

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  3. 薬局で妊産婦の薬の一元的・継続的な把握を...
  4. 薬を交付した薬局薬剤師の言い分 (日経B...

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Germinal center B and follicular helper T cells: siblings, cousins or just good friends?

著者 Nutt SL , Tarlinton DM
Nat Immunol.2011 Jun ; 12(6):472-7.
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The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. nutt@wehi.edu.au

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Humoral immunity requires interaction between specialized populations of B cells and CD4(+) T cells, called follicular helper T cells (T(FH) cells), in the germinal center (GC) to produce memory B cells and long-lived plasma cells. Molecular crosstalk between GC B cells and T(FH) cells influences the survival, proliferation and differentiation of each cell type. This pairing of GC B cells and T(FH) cells also occurs at the transcriptional level as the Bcl-6–IRF4–Blimp-1 axis, which is crucial for B cell differentiation, is also essential for the T(FH) cell identity. Less is known about the memory B cells that arise from the GC pool, as they seem to be distinctly 'programmed' on the basis of their antigen receptor affinity to enter the long-lived memory pool.
PMID: 21739669 [PubMed - in process]
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